Enhancers in the Peril lincRNA locus regulate distant but not local genes

Enhancers in the Peril lincRNA locus regulate distant but not local genes

Abstract Background Recently, it has become clear that some promoters function as long-range regulators of gene expression. However, direct and quantitative assessment of enhancer activity at long intergenic noncoding RNA (lincRNA) or mRNA gene bodies has not been performed. To unbiasedly assess the...

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Bibliographic Details
Main Authors: Abigail F. Groff, A. Rasim Barutcu, Jordan P. Lewandowski, John L. Rinn
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Genome Biology
Subjects:
lincRNA
Mouse models
MPRA
Cis-regulation
Enhancer
Online Access:http://link.springer.com/article/10.1186/s13059-018-1589-8

Internet

http://link.springer.com/article/10.1186/s13059-018-1589-8

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