RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection.

RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection.

The type I interferon pathway plays a critical role in both host defense and tolerance against viral infection and thus requires refined regulatory mechanisms. RIPK3-mediated necroptosis has been shown to be involved in anti-viral immunity. However, the exact role of RIPK3 in immunity to Influenza A...

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Bibliographic Details
Main Authors: Jeffrey Downey, Erwan Pernet, François Coulombe, Benoit Allard, Isabelle Meunier, Joanna Jaworska, Salman Qureshi, Donald C Vinh, James G Martin, Philippe Joubert, Maziar Divangahi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5406035?pdf=render

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http://europepmc.org/articles/PMC5406035?pdf=render

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