Combined quantitation of HMGA2 mRNA, microRNAs, and mitochondrial-DNA content enables the identification and typing of thyroid tumors in fine-needle aspiration smears

Combined quantitation of HMGA2 mRNA, microRNAs, and mitochondrial-DNA content enables the identification and typing of thyroid tumors in fine-needle aspiration smears

Abstract Background Analysis of molecular markers in addition to cytological analysis of fine-needle aspiration (FNA) samples is a promising way to improve the preoperative diagnosis of thyroid nodules. Nonetheless, in clinical practice, applications of existing diagnostic solutions based on the det...

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Bibliographic Details
Main Authors: Sergei E. Titov, Mikhail K. Ivanov, Pavel S. Demenkov, Gevork A. Katanyan, Eugenia S. Kozorezova, Anastasia V. Malek, Yulia A. Veryaskina, Igor F. Zhimulev
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
Thyroid carcinoma
preoperative diagnosis
molecular markers
HMGA2
microRNA
Online Access:http://link.springer.com/article/10.1186/s12885-019-6154-7

Internet

http://link.springer.com/article/10.1186/s12885-019-6154-7

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