Identification of Hyper-Methylated Tumor Suppressor Genes-Based Diagnostic Panel for Esophageal Squamous Cell Carcinoma (ESCC) in a Chinese Han Population

Identification of Hyper-Methylated Tumor Suppressor Genes-Based Diagnostic Panel for Esophageal Squamous Cell Carcinoma (ESCC) in a Chinese Han Population

DNA methylation-based biomarkers were suggested to be promising for early cancer diagnosis. However, DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC), especially in Chinese Han populations have not been identified and evaluated quantitatively. Candidate tumor suppressor...

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Bibliographic Details
Main Authors: Chenji Wang, Weilin Pu, Dunmei Zhao, Yinghui Zhou, Ting Lu, Sidi Chen, Zhenglei He, Xulong Feng, Ying Wang, Caihua Li, Shilin Li, Li Jin, Shicheng Guo, Jiucun Wang, Minghua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Genetics
Subjects:
esophageal squamous cell carcinoma (ESCC)
DNA methylation
biomarker
diagnosis
targeted bisulfite sequencing (TGS)
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00356/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00356/full

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