The Impaired Bioenergetics of Diabetic Cardiac Microvascular Endothelial Cells

Diabetes causes hyperglycemia, which can create a stressful environment for cardiac microvascular endothelial cells (CMECs). To investigate the impact of diabetes on the cellular metabolism of CMECs, we assessed glycolysis by quantifying the extracellular acidification rate (ECAR), and mitochondrial...

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Bibliographic Details
Main Authors: Haitao Zhang, Yan Shen, Il-man Kim, Neal L. Weintraub, Yaoliang Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.642857/full