Correlates of Protection for M Protein-Based Vaccines against Group A Streptococcus

Group A streptococcus (GAS) is known to cause a broad spectrum of illness, from pharyngitis and impetigo, to autoimmune sequelae such as rheumatic heart disease, and invasive diseases. It is a significant cause of infectious disease morbidity and mortality worldwide, but no efficacious vaccine is cu...

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Bibliographic Details
Main Authors: Shu Ki Tsoi, Pierre R. Smeesters, Hannah R. C. Frost, Paul Licciardi, Andrew C. Steer
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/167089