Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies
The environmental and metabolic pressures in the tumor microenvironment (TME) play a key role in molding tumor development by impacting the stromal and immune cell fractions, TME composition and activation. Hypoxia triggers a cascade of events that promote tumor growth, enhance resistance to the ant...
Main Authors: | Raefa Abou Khouzam, Klaudia Brodaczewska, Aleksandra Filipiak, Nagwa Ahmed Zeinelabdin, Stephanie Buart, Cezary Szczylik, Claudine Kieda, Salem Chouaib |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-01-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.613114/full |
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