Control of Long-Term Synaptic Potentiation and Learning by Alternative Splicing of the NMDA Receptor Subunit GluN1

Summary: NMDA receptors (NMDARs) are critical for physiological synaptic plasticity, learning, and memory and for pathological plasticity and neuronal death. The GluN1 subunit is encoded by a single gene, GRIN1, with 8 splice variants, but whether the diversity generated by this splicing has physiol...

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Bibliographic Details
Main Authors: Ameet S. Sengar, Hongbin Li, Wenbo Zhang, Celeste Leung, Arun K. Ramani, Ner Mu Saw, Yongqian Wang, YuShan Tu, P. Joel Ross, Stephen W. Scherer, James Ellis, Michael Brudno, Zhengping Jia, Michael W. Salter
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719315852