The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood–brain barrier formation and maturation

The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood–brain barrier formation and maturation

The blood–brain barrier (BBB) of Drosophila comprises a thin epithelial layer of subperineural glia (SPG), which ensheath the nerve cord and insulate it against the potassium-rich hemolymph by forming intercellular septate junctions (SJs). Previously, we identified a novel Gi/Go protein-coupled rece...

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Bibliographic Details
Main Authors: Xiaoling Li, Richard Fetter, Tina Schwabe, Christophe Jung, Liren Liu, Hermann Steller, Ulrike Gaul
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
blood-brain barrier
GPCR signaling
PKA
apical-basal polarity
septate junction
epithelium development
Online Access:https://elifesciences.org/articles/68275

Internet

https://elifesciences.org/articles/68275

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