Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF

Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF

Viruses often subvert the host immune system using molecular decoys to prevent an effective immune response. Here, the authors examine the structural details of the viral decoy receptor GIF and its antagnosim of GM-CSF and IL-2.

Bibliographic Details
Main Authors: Jan Felix, Eaazhisai Kandiah, Steven De Munck, Yehudi Bloch, Gydo C.P. van Zundert, Kris Pauwels, Ann Dansercoer, Katka Novanska, Randy J. Read, Alexandre M.J.J. Bonvin, Bjorn Vergauwen, Kenneth Verstraete, Irina Gutsche, Savvas N. Savvides
Format: Article
Language:English
Published: Nature Publishing Group 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13228

Internet

https://doi.org/10.1038/ncomms13228

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