Lacidipine Ameliorates the Endothelial Senescence and Inflammatory Injury Through CXCR7/P38/C/EBP-β Signaling Pathway

Lacidipine Ameliorates the Endothelial Senescence and Inflammatory Injury Through CXCR7/P38/C/EBP-β Signaling Pathway

Background: Lacidipine, a third-generation calcium channel blocker, exerts beneficial effects on the endothelium of hypertensive patients in addition to blood pressure lowering. However, the detailed mechanism underlying Lacidipine-related endothelial protection is still elusive.Methods: Sixteen spo...

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Bibliographic Details
Main Authors: Xing Liu, Zhuoshan Huang, Yuanyuan Zhang, Xing Shui, Fanmao Liu, Zhen Wu, Shiyue Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
lacidipine
oxidative stress
senescence
inflammation
CXCR7
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.692540/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.692540/full

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