Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV

Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV

Background: Visceral leishmaniasis (VL) treatment in HIV patients very often fails and is followed by high relapse and case-fatality rates. Hence, treatment efficacy assessment is imperative but based on invasive organ aspiration for parasite detection. In the search of a less-invasive alternative a...

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Bibliographic Details
Main Authors: Wim Adriaensen, Bart Cuypers, Carlota F. Cordero, Bewketu Mengasha, Séverine Blesson, Lieselotte Cnops, Paul M. Kaye, Fabiana Alves, Ermias Diro, Johan van Griensven
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:EBioMedicine
Subjects:
Visceral leishmaniasis
HIV
RNA signature
Treatment efficacy
Blood signature
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420301237

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http://www.sciencedirect.com/science/article/pii/S2352396420301237

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