The Multifactorial Role of PARP-1 in Tumor Microenvironment

The Multifactorial Role of PARP-1 in Tumor Microenvironment

Poly(ADP-ribose) polymerases (PARPs), represent a family of 17 proteins implicated in a variety of cell functions; some of them possess the enzymatic ability to synthesize and attach poly (ADP-ribose) (also known as PAR) to different protein substrates by a post-translational modification; PARPs are...

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Bibliographic Details
Main Authors: Juan Manuel Martí, Mónica Fernández-Cortés, Santiago Serrano-Sáenz, Esteban Zamudio-Martinez, Daniel Delgado-Bellido, Angel Garcia-Diaz, Francisco Javier Oliver
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
tumor microenvironment
parps
parylation
hypoxia
autophagy
parp inhibitors
Online Access:https://www.mdpi.com/2072-6694/12/3/739

Internet

https://www.mdpi.com/2072-6694/12/3/739

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