Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases
Caenorhabditis elegans has a number of distinct advantages that are useful for understanding the basis for cellular and organismal dysfunction underlying age-associated diseases of protein misfolding. Although protein aggregation, a key feature of human neurodegenerative diseases, has been typically...
Main Authors: | Carmen I. Nussbaum-Krammer, Richard I. Morimoto |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-01-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/7/1/31 |
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