Dental pulp stem cells differentiation reveals new insights in Oct4A dynamics.

Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog, and Oct4, in the maintenance of embryonic stem cell (ES) pluripotency and in the reprogramming of adult cells is well established, its persistence and function in adult stem cells are still debated....

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Main Authors: Federico Ferro, Renza Spelat, Federica D'Aurizio, Elisa Puppato, Maura Pandolfi, Antonio Paolo Beltrami, Daniela Cesselli, Giuseppe Falini, Carlo Alberto Beltrami, Francesco Curcio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3402417?pdf=render