A classification modeling approach for determining metabolite signatures in osteoarthritis.

Multiple factors can help predict knee osteoarthritis (OA) patients from healthy individuals, including age, sex, and BMI, and possibly metabolite levels. Using plasma from individuals with primary OA undergoing total knee replacement and healthy volunteers, we measured lysophosphatidylcholine (lyso...

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Bibliographic Details
Main Authors: Jason S Rockel, Weidong Zhang, Konstantin Shestopaloff, Sergei Likhodii, Guang Sun, Andrew Furey, Edward Randell, Kala Sundararajan, Rajiv Gandhi, Guangju Zhai, Mohit Kapoor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6025859?pdf=render