Preanalytical confounding factors in the analysis of cerebrospinal fluid biomarkers for Alzheimer’s disease: the issue of diurnal variation

Preanalytical confounding factors in the analysis of cerebrospinal fluid biomarkers for Alzheimer’s disease: the issue of diurnal variation

Given the growing use of cerebrospinal fluid (CSF) beta-amyloid (Aβ) and tau as biomarkers for early diagnosis of Alzheimer’s disease (AD), it is essential that the diagnostic procedures are standardized and the results comparable across different laboratories. Preanalytical factors are reported to...

Full description

Bibliographic Details
Main Authors: Claudia eCicognola, Davide eChiasserini, Lucilla eParnetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Neurology
Subjects:
Cerebrospinal Fluid
Circadian Rhythm
biomarkers
Alzheimer’s disease
confounding factors
Diurnal variability
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00143/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00143/full

Similar Items