Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives—Anticancer and Cholinesterase-Inhibiting Activity

Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives—Anticancer and Cholinesterase-Inhibiting Activity

The inverse correlation observed between Alzheimer’s disease (AD) and cancer has prompted us to look for cholinesterase-inhibiting activity in phenothiazine derivatives that possess anticancer properties. With the use of in silico and in vitro screening methods, our study found a new biological acti...

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Bibliographic Details
Main Authors: Jakub Jończyk, Justyna Godyń, Ewelina Stawarska, Beata Morak-Młodawska, Małgorzata Jeleń, Krystian Pluta, Barbara Malawska
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
cholinesterase inhibitors
virtual screening
Alzheimer’s disease
anticancer agents
dipyridothiazines
quinobenzothiazine
Online Access:https://www.mdpi.com/1420-3049/25/11/2604

Internet

https://www.mdpi.com/1420-3049/25/11/2604

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