Cytotoxic Effect of Trabectedin In Human Adrenocortical Carcinoma Cell Lines and Primary Cells

Cytotoxic Effect of Trabectedin In Human Adrenocortical Carcinoma Cell Lines and Primary Cells

Mitotane is the only drug approved for the treatment of adrenocortical carcinoma (ACC). The regimen to be added to mitotane is a chemotherapy including etoposide, doxorubicin, and cisplatin. This pharmacological approach, however, has a limited efficacy and significant toxicity. Evidence indicates t...

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Bibliographic Details
Main Authors: Andrea Abate, Elisa Rossini, Sara Anna Bonini, Martina Fragni, Deborah Cosentini, Guido Albero Massimo Tiberio, Diego Benetti, Constanze Hantel, Marta Laganà, Salvatore Grisanti, Massimo Terzolo, Maurizio Memo, Alfredo Berruti, Sandra Sigala
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
trabectedin
adrenocortical carcinoma
cytotoxicity
in vitro
cell lines
primary cell cultures
Online Access:https://www.mdpi.com/2072-6694/12/4/928

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https://www.mdpi.com/2072-6694/12/4/928

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