Isatin-Hydrazones with Multiple Receptor Tyrosine Kinases (RTKs) Inhibitory Activity and In-Silico Binding Mechanism

Recently, we have reported a series of isatin hydrazone, two of them, namely, 3-((2,6-dichlorobenzylidene)hydrazono)indolin-2-one (<b>1</b>) and 3-((2-chloro-6-fluorobenzylidene)hydrazono)indolin-2-one (<b>2</b>) having potent cytotoxicity, showing cyclin-dependent kinases (C...

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Bibliographic Details
Main Authors: Huda S. Al-Salem, Md Arifuzzaman, Iman S. Issa, A. F. M. Motiur Rahman
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/9/3746