Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity

<p>Abstract</p> <p>Background</p> <p>Activation of Toll-like receptors (TLRs) is widely accepted as an essential event for defence against infection. Many TLRs utilize a common signalling pathway that relies on activation of the kinase IRAK4 and the transcription factor...

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Bibliographic Details
Main Authors: Davidson Donald J, Gardy Jennifer L, Hamill Pamela, Kum Winnie, Falsafi Reza, Brown Kelly L, Turvey Stuart, Finlay Brett B, Speert David P, Hancock Robert EW
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/6