Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity
<p>Abstract</p> <p>Background</p> <p>Activation of Toll-like receptors (TLRs) is widely accepted as an essential event for defence against infection. Many TLRs utilize a common signalling pathway that relies on activation of the kinase IRAK4 and the transcription factor...
Main Authors: | Davidson Donald J, Gardy Jennifer L, Hamill Pamela, Kum Winnie, Falsafi Reza, Brown Kelly L, Turvey Stuart, Finlay Brett B, Speert David P, Hancock Robert EW |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-01-01
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Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/8/1/6 |
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