Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics

Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics

Abstract The recent global pandemic of the Coronavirus disease 2019 (COVID-19) caused by the new coronavirus SARS-CoV-2 presents an urgent need for the development of new therapeutic candidates. Many efforts have been devoted to screening existing drug libraries with the hope to repurpose approved d...

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Bibliographic Details
Main Authors: Hu Zhu, Catherine Z. Chen, Srilatha Sakamuru, Jinghua Zhao, Deborah K. Ngan, Anton Simeonov, Mathew D. Hall, Menghang Xia, Wei Zheng, Ruili Huang
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86110-8

Internet

https://doi.org/10.1038/s41598-021-86110-8

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