Efficient glycosylation site utilization by intracellular apolipoprotein B: implications for proteasomal degradation

Efficient glycosylation site utilization by intracellular apolipoprotein B: implications for proteasomal degradation

The balance between the hepatic assembly of apolipoprotein B (apoB) and its presecretory degradation at the level of the endoplasmic reticulum (ER) may control the secretion of apoB-containing lipoproteins. In one model, apoB that fails to assemble with lipid undergoes translocation arrest, exposing...

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Bibliographic Details
Main Authors: Xue F. Huang, Gregory S. Shelness
Format: Article
Language:English
Published: Elsevier 1999-12-01
Series:Journal of Lipid Research
Subjects:
endoplasmic reticulum
protein turnover
proteolysis
quality control
translocation
retrograde translocation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320964

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http://www.sciencedirect.com/science/article/pii/S0022227520320964

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