Effect of method of deduplication on estimation of differential gene expression using RNA-seq

Background RNA-seq is a useful tool for analysis of gene expression. However, its robustness is greatly affected by a number of artifacts. One of them is the presence of duplicated reads. Results To infer the influence of different methods of removal of duplicated reads on estimation of gene express...

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Bibliographic Details
Main Authors: Anna V. Klepikova, Artem S. Kasianov, Mikhail S. Chesnokov, Natalia L. Lazarevich, Aleksey A. Penin, Maria Logacheva
Format: Article
Language:English
Published: PeerJ Inc. 2017-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3091.pdf