Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis.

The stem-cell leukemia (SCL, also known as TAL1) gene encodes a basic helix-loop-helix transcription factor that is essential for the initiation of primitive and definitive hematopoiesis, erythrocyte and megakarocyte differentiation, angiogenesis, and astrocyte development. Here we report that the z...

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Bibliographic Details
Main Authors: Feng Qian, Fenghua Zhen, Jin Xu, Mei Huang, Wanyu Li, Zilong Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1858710?pdf=render