Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus.

Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus.

The SCL (TAL1) transcription factor is a critical regulator of haematopoiesis and its expression is tightly controlled by multiple cis-acting regulatory elements. To elaborate further the DNA elements which control its regulation, we used genomic tiling microarrays covering 256 kb of the human SCL l...

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Bibliographic Details
Main Authors: Pawandeep Dhami, Alexander W Bruce, Johanna H Jim, Shane C Dillon, Amanda Hall, Jonathan L Cooper, Nicolas Bonhoure, Kelly Chiang, Peter D Ellis, Cordelia Langford, Robert M Andrews, David Vetrie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2816701?pdf=render

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http://europepmc.org/articles/PMC2816701?pdf=render

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