Enhancement of α-Mangostin Wound Healing Ability by Complexation with 2-Hydroxypropyl-β-Cyclodextrin in Hydrogel Formulation

Enhancement of α-Mangostin Wound Healing Ability by Complexation with 2-Hydroxypropyl-β-Cyclodextrin in Hydrogel Formulation

α-Mangostin (α-M), one of the active compounds in <i>Garcinia mangostana</i> peel, has been effectively used in wound healing. However, its poor solubility in aqueous solution causes low bioavailability for skin ulcers, hindering its application in wound healing. The aim of this study wa...

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Bibliographic Details
Main Authors: Nasrul Wathoni, Diah Permata Sari, Ine Suharyani, Keiichi Motoyama, Ahmed Fouad Abdelwahab Mohammed, Arief Cahyanto, Marline Abdassah, Muchtaridi Muchtaridi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceuticals
Subjects:
α-Mangostin
hydroxypropyl-β-cyclodextrin
inclusion complex
hydrogel
wound healing
Online Access:https://www.mdpi.com/1424-8247/13/10/290

Internet

https://www.mdpi.com/1424-8247/13/10/290

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