The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1β

<p>Abstract</p> <p>Background</p> <p>Cartilage loss is a hallmark of arthritis and follows activation of catabolic processes concomitant with a disruption of anabolic pathways like insulin-like growth factor 1 (IGF-1). We hypothesized that two natural products of South...

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Bibliographic Details
Main Authors: Bobrowski Paul, Ahmed Salahuddin, Miller Mark JS, Haqqi Tariq M
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Complementary and Alternative Medicine
Online Access:http://www.biomedcentral.com/1472-6882/6/13