Differential effects of thymoquinone on lysophosphatidic acid-induced oncogenic pathways in ovarian cancer cells

Thymoquinone, a therapeutic phytochemical derived from Nigella sativa, has been shown to have a potent anticancer activity. However, it has been identified that the tumor microenvironment (TME) can attenuate the anticancer effects of thymoquinone (TQ) in ovarian cancer. Lysophosphatidic acid (LPA),...

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Bibliographic Details
Main Authors: Ji Hee Ha, Muralidharan Jayaraman, Rangasudhagar Radhakrishnan, Rohini Gomathinayagam, Mingda Yan, Yong Sang Song, Ciro Isidoro, Danny N. Dhanasekaran
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
LPA
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411020301590