Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine.

Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine.

Androgen insensitivity syndrome (AIS) is a rare disease associated with inactivating mutations of AR that disrupt male sexual differentiation, and cause a spectrum of phenotypic abnormalities having as a common denominator loss of reproductive viability. No established treatment exists for these con...

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Bibliographic Details
Main Authors: Adam T Szafran, Sean Hartig, Huiying Sun, Ivan P Uray, Maria Szwarc, Yuqing Shen, Sanjay N Mediwala, Jennifer Bell, Michael J McPhaul, Michael A Mancini, Marco Marcelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2785468?pdf=render

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http://europepmc.org/articles/PMC2785468?pdf=render

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