Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques

Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques

Abstract An effective vaccine to prevent HIV transmission has not yet been achieved. Modulation of the microbiome via probiotic therapy has been suggested to result in enhanced mucosal immunity. Here, we evaluated whether probiotic therapy could improve the immunogenicity and protective efficacy of...

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Bibliographic Details
Main Authors: Nichole R. Klatt, Courtney Broedlow, Jessica M. Osborn, Andrew T. Gustin, Sandra Dross, Megan A. O’Connor, Ernesto Coronado, Philip Barnette, Tiffany Hensley-McBain, Alexander S. Zevin, Roshell Muir, Alexander Roederer, Solomon Wangari, Naoto Iwayama, Chul Y. Ahrens, Jeremy Smedley, Cassandra Moats, Rebecca M. Lynch, Elias K. Haddad, Nancy L. Haigwood, Deborah H. Fuller, Jennifer A. Manuzak
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00298-4

Internet

https://doi.org/10.1038/s41541-021-00298-4

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