Association of mitochondrial genetic variation with carotid atherosclerosis.

In human pathology, several diseases are associated with somatic mutations in the mitochondrial genome (mtDNA). Even though mitochondrial dysfunction leads to increased oxidative stress, the role of mitochondrial mutations in atherosclerosis has not received much attention so far. In this study we a...

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Bibliographic Details
Main Authors: Igor A Sobenin, Margarita A Sazonova, Anton Y Postnov, Jukka T Salonen, Yuri V Bobryshev, Alexander N Orekhov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706616?pdf=render