TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection

TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection

Toll-like receptor 7 (TLR7) known to recognize guanidine-rich ssRNA has been shown to mount vital host defense mechanism against many viruses including flaviviruses. Signal transduction through TLR7 has been shown to produce type-1 interferon and proinflammatory mediators, thereby initiating essenti...

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Bibliographic Details
Main Authors: Arshed Nazmi, Sriparna Mukherjee, Kiran Kundu, Kallol Dutta, Anita Mahadevan, Susarla Krishna Shankar, Anirban Basu
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Neurobiology of Disease
Subjects:
Pattern recognition receptors
Neurons
Innate immunity
Japanese encephalitis
Antiviral
Neurotrophic virus
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001545

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http://www.sciencedirect.com/science/article/pii/S0969996114001545

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