Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities

Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities

Summary: Human induced pluripotent stem cells (hiPSCs) can generate a multiplicity of organoids, yet no compelling evidence currently exists as to whether or not these contain tissue-specific, holoclone-forming stem cells. Here, we show that a subpopulation of cells in a hiPSC-derived corneal epithe...

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Bibliographic Details
Main Authors: Shinya Watanabe, Ryuhei Hayashi, Yuzuru Sasamoto, Motokazu Tsujikawa, Bruce R. Ksander, Markus H. Frank, Andrew J. Quantock, Natasha Y. Frank, Kohji Nishida
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Bioengineering
Cell biology
Stem cells research
Tissue engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221006568

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http://www.sciencedirect.com/science/article/pii/S2589004221006568

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