Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy

<p>Abstract</p> <p>Background</p> <p>Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect. One strategy targeting this metabolic phenotype is glucose restriction by administrati...

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Bibliographic Details
Main Authors: Mueller-Klieser Wolfgang, Walenta Stefan, Hattingen Elke, Harter Patrick N, Bähr Oliver, Brucker Daniel P, Maurer Gabriele D, Steinbach Joachim P, Rieger Johannes
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/315