A sex-specific reconstitution bias in the competitive CD45.1/CD45.2 congenic bone marrow transplant model

Abstract Allelic variants of the pan-haematopoietic cell marker CD45, identified as CD45.1 and CD45.2, have been established as a marker system to track haematopoietic cells following congenic mouse bone marrow transplants. Despite the frequent use of this model for studying the impact of genetic mo...

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Bibliographic Details
Main Authors: Salema Jafri, Stephen D. Moore, Nicholas W. Morrell, Mark L. Ormiston
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03784-9