PKM2 promotes reductive glutamine metabolism

PKM2 promotes reductive glutamine metabolism

<b>Objective:</b> Pyruvate kinases M (PKM), including the PKM1 and PKM2 isoforms, are critical factors in glucose metabolism. PKM2 promotes aerobic glycolysis, a phenomenon known as “the Warburg effect”. The purpose of this study was to identify the roles of PKM2 in regulating cellular...

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Bibliographic Details
Main Authors: Miao Liu, Yuanyuan Wang, Yuxia Ruan, Changsen Bai, Li Qiu, Yanfen Cui, Guoguang Ying, Binghui Li
Format: Article
Language:English
Published: China Anti-Cancer Association 2018-12-01
Series:Cancer Biology & Medicine
Subjects:
The Warburg effect
the reverse Warburg effect
PKM2
glucose metabolism
proton homeostasis
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1288

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1288

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