Heterogeneous Effects of Fibroblast-Myocyte Coupling in Different Regions of the Human Atria Under Conditions of Atrial Fibrillation

Heterogeneous Effects of Fibroblast-Myocyte Coupling in Different Regions of the Human Atria Under Conditions of Atrial Fibrillation

Background: Atrial fibrillation (AF), the most common cardiac arrhythmia, is characterized by alteration of the action potential (AP) propagation. Under persistent AF, myocytes undergo electrophysiological and structural remodeling, which involves fibroblast proliferation and differentiation, modify...

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Bibliographic Details
Main Authors: Jorge Sánchez, Juan F. Gomez, Laura Martinez-Mateu, Lucia Romero, Javier Saiz, Beatriz Trenor
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Physiology
Subjects:
atrial fibrillation
computer simulation
structural remodeling
myofibroblast
vulnerability
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00847/full

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https://www.frontiersin.org/article/10.3389/fphys.2019.00847/full

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