VEGF-A Stimulates STAT3 Activity via Nitrosylation of Myocardin to Regulate the Expression of Vascular Smooth Muscle Cell Differentiation Markers

VEGF-A Stimulates STAT3 Activity via Nitrosylation of Myocardin to Regulate the Expression of Vascular Smooth Muscle Cell Differentiation Markers

Abstract Vascular endothelial growth factor A (VEGF-A) is a pivotal player in angiogenesis. It is capable of influencing such cellular processes as tubulogenesis and vascular smooth muscle cell (VSMC) proliferation, yet very little is known about the actual signaling events that mediate VEGF-A induc...

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Bibliographic Details
Main Authors: Xing Hua Liao, Yuan Xiang, Hui Li, De Liang Zheng, Yao Xu, Cheng Xi Yu, Jia Peng Li, Xiao Yu Zhang, Wei Bin Xing, Dong Sun Cao, Le Yuan Bao, Tong Cun Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02907-6

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https://doi.org/10.1038/s41598-017-02907-6

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