Rapamycin Ameliorates Proteinuria and Restores Nephrin and Podocin Expression in Experimental Membranous Nephropathy

Objective. Recent studies have shown a beneficial effect of rapamycin in passive and active Heymann Nephritis (HN). However, the mechanisms underlying this beneficial effect have not been elucidated. Methods. Passive Heymann Nephritis (PHN) was induced by a single intravenous infusion of anti-Fx1 in...

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Main Authors: Stavros Stratakis, Kostas Stylianou, Ioannis Petrakis, Vasiliki Mavroeidi, Rafaela Poulidaki, Christina Petra, Demitrios Moisiadis, Spyros Stratigis, Eleftheria Vardaki, Lydia Nakopoulou, Eugene Daphnis
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/941893