JAK/STAT3 regulated global gene expression dynamics during late-stage reprogramming process

Abstract Background The generation of induced pluripotent stem cells (iPSCs) has underdefined mechanisms. In addition, leukemia inhibitory factor (LIF) activated Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway is the master regulator for naïve-state pluripotency a...

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Bibliographic Details
Main Authors: Ling Wang, Zongliang Jiang, Delun Huang, Jingyue Duan, Chang Huang, Shannon Sullivan, Kaneha Vali, Yexuan Yin, Ming Zhang, Jill Wegrzyn, Xiuchun ( Cindy) Tian, Young Tang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Genomics
Subjects:
LIF
Online Access:http://link.springer.com/article/10.1186/s12864-018-4507-2