Cleavage of the HPV16 Minor Capsid Protein L2 during Virion Morphogenesis Ablates the Requirement for Cellular Furin during De Novo Infection

Infections by high-risk human papillomaviruses (HPV) are the causative agents for the development of cervical cancer. As with other non-enveloped viruses, HPVs are taken up by the cell through endocytosis following primary attachment to the host cell. Through studies using recombinant pseudovirus pa...

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Bibliographic Details
Main Authors: Linda Cruz, Jennifer Biryukov, Michael J. Conway, Craig Meyers
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/11/2910