High expression of IDO1 and TGF-β1 during recurrence and post infection clearance with Chlamydia trachomatis, are independent of host IFN-γ response

High expression of IDO1 and TGF-β1 during recurrence and post infection clearance with Chlamydia trachomatis, are independent of host IFN-γ response

Abstract Background Chlamydia trachomatis infections in women continue to be a major public health concern due to their high prevalence and consequent reproductive morbidities. While antibiotics are usually efficient to clear the Chlamydia, repeat infections are common and may contribute to patholog...

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Bibliographic Details
Main Authors: Noa Ziklo, Wilhelmina M. Huston, Kuong Taing, Peter Timms
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Infectious Diseases
Subjects:
Chlamydia trachomatis
Indoleamine 2,3-dioxygenase
Interferon-gamma
Tryptophan
Kynurenine
Regulatory immune response
Online Access:http://link.springer.com/article/10.1186/s12879-019-3843-4

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http://link.springer.com/article/10.1186/s12879-019-3843-4

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