Alterations in energy metabolism, neuroprotection and visual signal transduction in the retina of Parkinsonian, MPTP-treated monkeys.

Parkinson disease is mainly characterized by the degeneration of dopaminergic neurons in the central nervous system, including the retina. Different interrelated molecular mechanisms underlying Parkinson disease-associated neuronal death have been put forward in the brain, including oxidative stress...

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Bibliographic Details
Main Authors: Laura Campello, Julián Esteve-Rudd, Roque Bru-Martínez, María Trinidad Herrero, Emiliano Fernández-Villalba, Nicolás Cuenca, José Martín-Nieto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3764107?pdf=render