Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

Drosophila Lnk is the single ancestral orthologue of a highly conserved family of structurally-related intracellular adaptor proteins, the SH2B proteins. As adaptors, they lack catalytic activity but contain several protein-protein interaction domains, thus playing a critical role in signal transduc...

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Bibliographic Details
Main Authors: Cathy Slack, Christian Werz, Daniela Wieser, Nazif Alic, Andrea Foley, Hugo Stocker, Dominic J Withers, Janet M Thornton, Ernst Hafen, Linda Partridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2841611?pdf=render

Internet

http://europepmc.org/articles/PMC2841611?pdf=render

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