Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-κB in immortalized and malignant oral keratinocytes

<p>Abstract</p> <p>Background</p> <p>Interleukin-8 (IL-8) is a cytokine that plays an important role in tumor progression in a variety of cancer types; however, its regulation is not well understood in oral cancer cells. In the present study, we examined the expression...

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Bibliographic Details
Main Authors: Lee Suk-Keun, Lee Sun-Kyung, Lee Jun, Lee Hwa-Jeong, Kim Eun-Cheol
Format: Article
Language:English
Published: BMC 2007-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/176