Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection.

Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection.

Burden of pneumonia caused by Streptococcus pneumoniae remains high despite the availability of conjugate vaccines. Mucosal immunization targeting the lungs is an attractive alternative for the induction of local immune responses to improve protection against pneumonia. Our group had previously desc...

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Bibliographic Details
Main Authors: Tasson C Rodrigues, Maria Leonor S Oliveira, Alessandra Soares-Schanoski, Stefanni L Chavez-Rico, Douglas B Figueiredo, Viviane M Gonçalves, Daniela M Ferreira, Nitesh K Kunda, Imran Y Saleem, Eliane N Miyaji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5779684?pdf=render

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http://europepmc.org/articles/PMC5779684?pdf=render

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