IFNβ1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment

IFNβ1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment

Chemotherapy (CTX) remains the standard of care for most aggressive tumours, including breast cancer (BC). In BC chemotherapeutic regimens, the maximum tolerated dose of cytotoxic drugs is administered at regular intervals, and cancer cells can re‐grow or adapt during the resting periods between cyc...

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Bibliographic Details
Main Authors: Ana Maia, Zuguang Gu, André Koch, Mireia Berdiel‐Acer, Rainer Will, Matthias Schlesner, Stefan Wiemann
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Molecular Oncology
Subjects:
breast cancer
chemotherapy
fibroblasts
IFNβ1
tumour microenvironment
Online Access:https://doi.org/10.1002/1878-0261.12905

Internet

https://doi.org/10.1002/1878-0261.12905

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