Impact of tissue transport on PET hypoxia quantification in pancreatic tumours

Impact of tissue transport on PET hypoxia quantification in pancreatic tumours

Abstract Background The clinical impact of hypoxia in solid tumours is indisputable and yet questions about the sensitivity of hypoxia-PET imaging have impeded its uptake into routine clinical practice. Notably, the binding rate of hypoxia-sensitive PET tracers is slow, comparable to the rate of dif...

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Bibliographic Details
Main Authors: Edward Taylor, Jennifer Gottwald, Ivan Yeung, Harald Keller, Michael Milosevic, Neesha C. Dhani, Iram Siddiqui, David W. Hedley, David A. Jaffray
Format: Article
Language:English
Published: SpringerOpen 2017-12-01
Series:EJNMMI Research
Subjects:
Positron emission tomography
Hypoxia imaging
PET tracer kinetic modelling
Online Access:http://link.springer.com/article/10.1186/s13550-017-0347-3

Internet

http://link.springer.com/article/10.1186/s13550-017-0347-3

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